Why does cirrhosis affect the brain so dramatically?
The Common Good

Why does cirrhosis affect the brain so dramatically?

The prevalence of liver disease in Australia is estimated to be 6 million and this is set to continue to increase over the next 15 years and beyond. Healthcare professionals know that with an increase in liver disease there will be an increase of patients with cirrhosis.

Hepatic encephalopathy presents occurs as a result of cirrhosis – severe liver disease. Severe onset often causes extreme personality changes, confusion, confused speech, anxiety and lethargy in patients and can develop into coma and even death.

This debilitating decline in brain function not only has a major effect on prognosis and quality life of patients, it also has an impact on families and the health care system, yet little is understood about this disease and its effects on the body and brain.

Dr Tony Rahman is studying hepatic encephalopathy in a bid to better understand the underlying causes and development of this disease, which, in turn, will improve clinician’s ability to reach a diagnosis and potentially treatment and patient outcomes in future.

The Prince Charles Hospital

Support The Common Good here.

Published: April 26, 2019

Related news & events

Meet the 2025 PhD Recipients

Research Grants

Meet the 2025 PhD Recipients

The Prince Charles Hospital Foundation was pleased to award six PhD Scholarships in 2025. Click here to meet the recipients.

Find out more

Professor Gregory Scalia AM

Researcher Stories

Professor Gregory Scalia AM

Professor Gregory Scalia AMProfessor Gregory Scalia AM first stepped into The Prince Charles Hospital as a registrar in the early 90s. Now, as the hospital’s long-standing Director of Echocardiography, he has dedicated most of his career to ensuring that complex cardiac diagnoses are accessible to a much larger portion of the population through echocardiography

Find out more

Meet the 2025 Research Fellowship Recipients

Research Grants

Meet the 2025 Research Fellowship Recipients

In this blog, we introduce you to our 2025 Research Fellowship recipients and share insights into their work and why their investigations are so important.

Find out more

Key Indicators of Cognitive Impairment in Patients with Obstructive Sleep Apnoea

Ageing

Key Indicators of Cognitive Impairment in Patients with Obstructive Sleep Apnoea

“There’s emerging evidence that links poor sleep to the development of dementia – particularly Alzheimer’s disease,” said Dr Irene Szollosi.

Find out more

Carl Francia, PhD candidate

Researcher Stories

Carl Francia, PhD candidate

PhD candidate Carl Francia first observed the disproportionate impact of Acute Rheumatic Fever and RHD on Indigenous Australians while working as a physiotherapist in 2022.

Find out more

TPCH Researcher of the Year 2024, Dr Ieuan Evans

Researcher Stories

TPCH Researcher of the Year 2024, Dr Ieuan Evans

TPCH Researcher of the Year 2024, Dr Ieuan Evans, is working to develop a Therapeutic Drug Monitoring (TDM) program specifically for Trikafta.

Find out more

Enhancing patient recovery with Memory Lane 

Ageing

Enhancing patient recovery with Memory Lane 

The hospital’s Occupational Therapy department enlisted the help of some fourth-year UQ students to complete a joint project aimed at promoting Memory Lane and gathering feedback on its usage.

Find out more

Jacarandas and The Prince Charles Hospital

The Common Good

Jacarandas and The Prince Charles Hospital

Over the past several decades on The Prince Charles Hospital’s campus, Jacaranda trees have offered shade and shelter from the elements, as well as a beautiful spot for people to gather outside the clinical environments.

Find out more

The Prince Charles Hospital’s 2025 Giving Day

The Common Good

The Prince Charles Hospital’s 2025 Giving Day

Over $162,000 was raised for The Prince Charles Hospital at our fifth annual Giving Day, thanks to our special community.

Find out more